Despite

Part of speech: noun (n.)

1. Malice; malignity; spite; malicious anger; contemptuous hate. With all thy despite against the land of Israel. Ezek. xxv. 6.

2. An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt. A despite done against the Most High. Milton. In despite, in defiance of another's power or inclination. -- In despite of, in defiance of; in spite of. See under Spite. "Seized my hand in despite of my efforts to the contrary." W. Irving. -- In your despite, in defiance or contempt of you; in spite of you. [Obs.]

Part of speech: verb (v.)

To vex; to annoy; to offend contemptuously. [Obs.] Sir W. Raleigh.

Part of speech: preposition (prep.)

In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.

Synonyms: See Notwithstanding.